Heart Failure Pathophysiology and Diagnosis

Pathophysiology In an average healthy person, normal LV ejection fraction (LVEF): ¬†>50% Roughly 50% of those with heart failure have reduced left ventricular (LV) function¬†(HFrEF) Heart cannot squeeze/contract properly, and then progressively dilates. The other 50% have preserved (normal contraction) LV function (HFpEF) Cannot relax properly, leading to high diastolic (filling) pressures. New heart failure …

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